Mitragynine, an euphoric compound inhibits hERG1a/1b channel current and upregulates the complexation of hERG1a-Hsp90 in HEK293-hERG1a/1b cells

Mitragyna speciosa Korth (M. speciosa) has been widely used as a recreational product, however, there are growing concerns on the abuse potentials and toxicity of the plant. Several poisoning and fatal cases involving kratom and mitragynine have been reported but the underlying causes remain unclear...

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Detalles Bibliográficos
Autores principales: Tay, Yea Lu, Amanah, Azimah, Adenan, Mohd Ilham, Wahab, Habibah Abdul, Tan, Mei Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930223/
https://www.ncbi.nlm.nih.gov/pubmed/31874991
http://dx.doi.org/10.1038/s41598-019-56106-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930223/
https://www.ncbi.nlm.nih.gov/pubmed/31874991
http://dx.doi.org/10.1038/s41598-019-56106-6

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