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Collagen fragments quantified in serum as measures of desmoplasia associate with survival outcome in patients with advanced pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular...

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Detalles Bibliográficos
Autores principales: Willumsen, Nicholas, Ali, Suhail M., Leitzel, Kim, Drabick, Joseph J., Yee, Nelson, Polimera, Hyma V., Nagabhairu, Vinod, Krecko, Laura, Ali, Ayesha, Maddukuri, Ashok, Moku, Prashanth, Ali, Aamnah, Poulose, Joyson, Menon, Harry, Pancholy, Neha, Costa, Luis, Karsdal, Morten A., Lipton, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930304/
https://www.ncbi.nlm.nih.gov/pubmed/31875000
http://dx.doi.org/10.1038/s41598-019-56268-3