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Collagen fragments quantified in serum as measures of desmoplasia associate with survival outcome in patients with advanced pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular...
Autores principales: | Willumsen, Nicholas, Ali, Suhail M., Leitzel, Kim, Drabick, Joseph J., Yee, Nelson, Polimera, Hyma V., Nagabhairu, Vinod, Krecko, Laura, Ali, Ayesha, Maddukuri, Ashok, Moku, Prashanth, Ali, Aamnah, Poulose, Joyson, Menon, Harry, Pancholy, Neha, Costa, Luis, Karsdal, Morten A., Lipton, Allan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930304/ https://www.ncbi.nlm.nih.gov/pubmed/31875000 http://dx.doi.org/10.1038/s41598-019-56268-3 |
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