The Protective Role of Tanshinone IIA in Silicosis Rat Model via TGF-β1/Smad Signaling Suppression, NOX4 Inhibition and Nrf2/ARE Signaling Activation

PURPOSE: Silicosis is an occupational disease caused by inhalation of silica and there are no effective drugs to treat this disease. Tanshinone IIA (Tan IIA), a traditional natural component, has been reported to possess anti-inflammatory, antioxidant, and anti-fibrotic properties. The current study...

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Detalles Bibliográficos
Autores principales: Feng, Feifei, Cheng, Peng, Zhang, Huanan, Li, Nannan, Qi, Yuxin, Wang, Hui, Wang, Yongbin, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930391/
https://www.ncbi.nlm.nih.gov/pubmed/31908414
http://dx.doi.org/10.2147/DDDT.S230572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930391/
https://www.ncbi.nlm.nih.gov/pubmed/31908414
http://dx.doi.org/10.2147/DDDT.S230572

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