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Aberrant CDK9 expression within chordoma tissues and the therapeutic potential of a selective CDK9 inhibitor LDC000067

Objectives: Chordomas are slow-growing malignancies that commonly affect vital neurological structures. These neoplasms are highly resistant to current chemotherapeutic regimens and often recur after surgical intervention. Therefore, there is an urgent need to identify molecular targets and more rob...

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Detalles Bibliográficos
Autores principales: Shen, Shen, Dean, Dylan C., Yu, Zujiang, Hornicek, Francis, Kan, Quancheng, Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930393/
https://www.ncbi.nlm.nih.gov/pubmed/31892980
http://dx.doi.org/10.7150/jca.35426