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Tankyrases/β-catenin Signaling Pathway as an Anti-proliferation and Anti-metastatic Target in Hepatocarcinoma Cell Lines

Objective: The Wnt/β-catenin pathway is involved in the development of hepatocellular carcinoma (HCC) and malignant events such as the epithelial-mesenchymal transition (EMT), metastasis, and invasion. Studies have illustrated that the inhibition of tankyrases (TNKS) antagonizes Wnt/β-catenin signal...

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Detalles Bibliográficos
Autores principales: Huang, Jianghai, Qu, Qiang, Guo, Yong, Xiang, Yuqi, Feng, Deyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930431/
https://www.ncbi.nlm.nih.gov/pubmed/31897238
http://dx.doi.org/10.7150/jca.30976