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Aptamers: A Review of Their Chemical Properties and Modifications for Therapeutic Application

Aptamers are short, single-stranded oligonucleotides that bind to specific target molecules. The shape-forming feature of single-stranded oligonucleotides provides high affinity and excellent specificity toward targets. Hence, aptamers can be used as analogs of antibodies. In December 2004, the US F...

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Detalles Bibliográficos
Autores principales: Adachi, Tatsuo, Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930564/
https://www.ncbi.nlm.nih.gov/pubmed/31766318
http://dx.doi.org/10.3390/molecules24234229