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Synthesis of Aryl Propionamide Scaffold Containing a Pentafluorosulfanyl Moiety as SARMs

The pentafluorosulfane (SF(5)) group, as a more electronegative bioisostere than the trifluoromethyl (CF(3)) group, has been gaining greater attention and increasingly reported usage in medicinal chemistry. Ostarine is the selective androgen receptor modulators (SARMs) containing a CF(3) group in cl...

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Detalles Bibliográficos
Autores principales: Shao, Pingxuan, Zhou, Yan, Yang, Dehua, Wang, Ming-Wei, Lu, Wei, Jin, Jiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930600/
https://www.ncbi.nlm.nih.gov/pubmed/31757115
http://dx.doi.org/10.3390/molecules24234227