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Synthesis of Aryl Propionamide Scaffold Containing a Pentafluorosulfanyl Moiety as SARMs
The pentafluorosulfane (SF(5)) group, as a more electronegative bioisostere than the trifluoromethyl (CF(3)) group, has been gaining greater attention and increasingly reported usage in medicinal chemistry. Ostarine is the selective androgen receptor modulators (SARMs) containing a CF(3) group in cl...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930600/ https://www.ncbi.nlm.nih.gov/pubmed/31757115 http://dx.doi.org/10.3390/molecules24234227 |