Matrix Metalloproteinase Triple-Helical Peptide Inhibitors: Potential Cross-Reactivity with Caspase-11

Triple-helical peptide inhibitors (THPIs) of matrix metalloproteinases (MMPs) have recently been demonstrated to be effective in a variety of animal models of disease, coincidental with knockout studies. However, passenger mutations have been described in MMP knockout mice that impact the activity o...

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Detalles Bibliográficos
Autores principales: Knapinska, Anna M., Hart, Melissa, Drotleff, Gary, Fields, Gregg B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930605/
https://www.ncbi.nlm.nih.gov/pubmed/31795279
http://dx.doi.org/10.3390/molecules24234355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930605/
https://www.ncbi.nlm.nih.gov/pubmed/31795279
http://dx.doi.org/10.3390/molecules24234355

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