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Matrix Metalloproteinase Triple-Helical Peptide Inhibitors: Potential Cross-Reactivity with Caspase-11
Triple-helical peptide inhibitors (THPIs) of matrix metalloproteinases (MMPs) have recently been demonstrated to be effective in a variety of animal models of disease, coincidental with knockout studies. However, passenger mutations have been described in MMP knockout mice that impact the activity o...
Autores principales: | Knapinska, Anna M., Hart, Melissa, Drotleff, Gary, Fields, Gregg B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930605/ https://www.ncbi.nlm.nih.gov/pubmed/31795279 http://dx.doi.org/10.3390/molecules24234355 |
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