Considerations on the Rational Design of Covalently Conjugated Cell-Penetrating Peptides (CPPs) for Intracellular Delivery of Proteins: A Guide to CPP Selection Using Glucarpidase as the Model Cargo Molecule

Access of proteins to their intracellular targets is limited by a hydrophobic barrier called the cellular membrane. Conjugation with cell-penetrating peptides (CPPs) has been shown to improve protein transduction into the cells. This conjugation can be either covalent or non-covalent, each with its...

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Detalles Bibliográficos
Autores principales: Behzadipour, Yasaman, Hemmati, Shiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930620/
https://www.ncbi.nlm.nih.gov/pubmed/31779220
http://dx.doi.org/10.3390/molecules24234318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930620/
https://www.ncbi.nlm.nih.gov/pubmed/31779220
http://dx.doi.org/10.3390/molecules24234318

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