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Glutathione Deficiency and Alterations in the Sulfur Amino Acid Homeostasis during Early Postnatal Development as Potential Triggering Factors for Schizophrenia-Like Behavior in Adult Rats

Impaired glutathione (GSH) synthesis and dopaminergic transmission are important factors in the pathophysiology of schizophrenia. Our research aimed to assess the effects of l-buthionine-(S,R)-sulfoximine (BSO), a GSH synthesis inhibitor, and GBR 12909, a dopamine reuptake inhibitor, administered al...

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Detalles Bibliográficos
Autores principales: Górny, Magdalena, Wnuk, Agnieszka, Kamińska, Adrianna, Kamińska, Kinga, Chwatko, Grażyna, Bilska-Wilkosz, Anna, Iciek, Małgorzata, Kajta, Małgorzata, Rogóż, Zofia, Lorenc-Koci, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930621/
https://www.ncbi.nlm.nih.gov/pubmed/31766654
http://dx.doi.org/10.3390/molecules24234253