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Solid-Phase Insertion of N-mercaptoalkylglycine Residues into Peptides

N-mercaptoalkylglycine residues were inserted into peptides by reacting N-free amino groups of peptides, which were initially synthesized on 2-chlorotrityl resin (Cltr) using the Fmoc/(t)Bu method, with bromoacetic acid and subsequent nucleophilic replacement of the bromide by reacting with S-4-meth...

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Detalles Bibliográficos
Autores principales: Mourtas, Spyridon, Gatos, Dimitrios, Barlos, Kleomenis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930625/
https://www.ncbi.nlm.nih.gov/pubmed/31766740
http://dx.doi.org/10.3390/molecules24234261