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Anti-Amyloidogenic Effects of Asarone Derivatives From Perilla frutescens Leaves Against Beta-Amyloid Aggregation and Nitric Oxide Production

Alzheimer’s disease (AD) is a progressive, neurodegenerative brain disorder associated with loss of memory and cognitive function. Beta-amyloid (Aβ) aggregates, in particular, are known to be highly neurotoxic and lead to neurodegeneration. Therefore, blockade or reduction of Aβ aggregation is a pro...

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Detalles Bibliográficos
Autores principales: Lee, Jae Eun, Kim, Nayeon, Yeo, Ji Yun, Seo, Dae-Gun, Kim, Sunggun, Lee, Jae-Sun, Hwang, Kwang Woo, Park, So-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930631/
https://www.ncbi.nlm.nih.gov/pubmed/31775356
http://dx.doi.org/10.3390/molecules24234297