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Enantioselective Synthesis of 8-Hydroxyquinoline Derivative, Q134 as a Hypoxic Adaptation Inducing Agent

Hypoxia is a common feature of neurodegenerative diseases, including Alzheimer’s disease that may be responsible for disease pathogenesis and progression. Therefore, the hypoxia-inducible factor (HIF)1 system, responsible for hypoxic adaptation, is a potential therapeutic target to combat these dise...

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Detalles Bibliográficos
Autores principales: Hackler, László, Gyuris, Márió, Huzián, Orsolya, Alföldi, Róbert, Szebeni, Gábor J., Madácsi, Ramóna, Knapp, Levente, Kanizsai, Iván, Puskás, László G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930632/
https://www.ncbi.nlm.nih.gov/pubmed/31771153
http://dx.doi.org/10.3390/molecules24234269