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Construction of Quantitative Structure Activity Relationship (QSAR) Models to Predict Potency of Structurally Diversed Janus Kinase 2 Inhibitors

Janus kinase 2 (JAK2) inhibitors represent a promising therapeutic class of anticancer agents against many myeloproliferative disorders. Bioactivity data on pIC [Formula: see text] of 2229 JAK2 inhibitors were employed in the construction of quantitative structure-activity relationship (QSAR) models...

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Detalles Bibliográficos
Autores principales:	Simeon, Saw, Jongkon, Nathjanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930640/ https://www.ncbi.nlm.nih.gov/pubmed/31805692 http://dx.doi.org/10.3390/molecules24234393

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