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Synthesis and Comparative Structure–Activity Study of Carbohydrate-Based Phenolic Compounds as α-Glucosidase Inhibitors and Antioxidants

Twenty-one natural and unnatural phenolic compounds containing a carbohydrate moiety were synthesized and their structure–activity relationship (SAR) was evaluated for α-glucosidase inhibition and antioxidative activity. Varying the position of the galloyl unit on the 1,5-anhydro-d-glucitol (1,5-AG)...

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Detalles Bibliográficos
Autores principales: Machida, Shota, Mukai, Saki, Kono, Rina, Funato, Megumi, Saito, Hiroaki, Uchiyama, Taketo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930660/
https://www.ncbi.nlm.nih.gov/pubmed/31783621
http://dx.doi.org/10.3390/molecules24234340