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Design and Synthesis of N-phenyl Phthalimides as Potent Protoporphyrinogen Oxidase Inhibitors

Protoporphyrinogen oxidase (PPO) has been identified as one of the most promising targets for herbicide discovery. A series of novel phthalimide derivatives were designed by molecular docking studies targeting the crystal structure of mitochondrial PPO from tobacco (mtPPO, PDB: 1SEZ) by using Flumio...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Li, Xiaotian, Ren, Da, Sun, Susu, Huo, Jingqian, Wang, Yanen, Chen, Lai, Zhang, Jinlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930678/
https://www.ncbi.nlm.nih.gov/pubmed/31795340
http://dx.doi.org/10.3390/molecules24234363