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Brain MRI Reveals Ascending Atrophy in Parkinson's Disease Across Severity

Models which assess the progression of Lewy pathology in Parkinson's disease have proposed ascending spread in a caudal-rostral pattern. In-vivo human evidence for this theory is limited, in part because there are no biomarkers that allow for direct assessment of Lewy pathology. Here, we measur...

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Detalles Bibliográficos
Autores principales: Blair, Jamie C., Barrett, Matthew J., Patrie, James, Flanigan, Joseph L., Sperling, Scott A., Elias, W. Jeffrey, Druzgal, T. Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930693/
https://www.ncbi.nlm.nih.gov/pubmed/31920949
http://dx.doi.org/10.3389/fneur.2019.01329