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Sildenafil Citrate Influences Production of TNF-α in Healthy Men Lymphocytes

The aim of our study was to determine whether sildenafil citrate influences the production of Th1- (TNF-α, INF-γ) or Th2-type (TGF-β, IL-10) cytokines by lymphocytes of healthy men. Sildenafil citrate (SC) is a selective blocker of phosphodiesterase 5, by competing for the binding site with cGMP. It...

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Detalles Bibliográficos
Autores principales: Zych, Michał, Roszczyk, Aleksander, Kniotek, Monika, Kaleta, Beata, Zagozdzon, Radoslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930755/
https://www.ncbi.nlm.nih.gov/pubmed/31915712
http://dx.doi.org/10.1155/2019/8478750