Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing

The CXCL12–CXCR4 axis plays a key role in the retention of stem cells and progenitors in dedicated bone marrow niches. It is well-known that CXCR4 responsiveness in B lymphocytes decreases dramatically during the final stages of their development in the bone marrow. However, the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Mcheik, Saria, Van Eeckhout, Nils, De Poorter, Cédric, Galés, Céline, Parmentier, Marc, Springael, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930800/
https://www.ncbi.nlm.nih.gov/pubmed/31921208
http://dx.doi.org/10.3389/fimmu.2019.02970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930800/
https://www.ncbi.nlm.nih.gov/pubmed/31921208
http://dx.doi.org/10.3389/fimmu.2019.02970

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