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Effects of Protective Mechanical Ventilation With Different PEEP Levels on Alveolar Damage and Inflammation in a Model of Open Abdominal Surgery: A Randomized Study in Obese Versus Non-obese Rats

Intraoperative positive end-expiratory pressure (PEEP) has been proposed to restore lung volumes and improve respiratory function in obesity. However, the biological impact of different PEEP levels on the lungs in obesity remains unknown. We aimed to compare the effects of PEEP = 2 cmH(2)O versus PE...

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Detalles Bibliográficos
Autores principales: Maia, Lígia de A., Fernandes, Marcos V. S., Santos, Raquel S., Agra, Laís C., Carvalho, Anna Carolinna, Rocha, Nazareth de N., Oliveira, Milena V., Santos, Cíntia L., Morales, Marcelo M., Capelozzi, Vera L., Souza, Sergio A. L., Gutfilen, Bianca, Schultz, Marcus J., Gama de Abreu, Marcelo, Pelosi, Paolo, Silva, Pedro L., Rocco, Patricia R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930834/
https://www.ncbi.nlm.nih.gov/pubmed/31920717
http://dx.doi.org/10.3389/fphys.2019.01513