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α-Synuclein regulation by chaperones in mammalian cells
Neurodegeneration in Parkinson’s disease is correlated with the occurrence of Lewy bodies, intracellular inclusions containing aggregates of the intrinsically disordered protein (IDP) α-Synuclein(1). The aggregation propensity of α-Synuclein in cells is modulated by specific factors including posttr...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930850/ https://www.ncbi.nlm.nih.gov/pubmed/31802003 http://dx.doi.org/10.1038/s41586-019-1808-9 |