Predicting Paclitaxel Disposition in Humans With Whole‐Body Physiologically‐Based Pharmacokinetic Modeling

Paclitaxel is a commonly used drug in the treatment of multiple solid tumors, including cancers of the breast, lung, and ovaries. Despite the established exposure–pharmacodynamic relationships for paclitaxel, treatment is associated with wide interindividual pharmacokinetic variability that leads to...

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Detalles Bibliográficos
Autores principales: Fu, Qiang, Sun, Xinxin, Lustburg, Maryam B., Sparreboom, Alex, Hu, Shuiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930855/
https://www.ncbi.nlm.nih.gov/pubmed/31671477
http://dx.doi.org/10.1002/psp4.12472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930855/
https://www.ncbi.nlm.nih.gov/pubmed/31671477
http://dx.doi.org/10.1002/psp4.12472

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