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JAK Inhibition Differentially Affects NK Cell and ILC1 Homeostasis

Janus kinase (JAK) inhibitors are widely used in the treatment of multiple autoimmune and inflammatory diseases. Immunologic and transcriptomic profiling have revealed major alterations on natural killer (NK) cell homeostasis associated with JAK inhibitions, while information on other innate lymphoi...

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Detalles Bibliográficos
Autores principales: Vian, Laura, Le, Mimi T., Gazaniga, Nathalia, Kieltyka, Jacqueline, Liu, Christine, Pietropaolo, Giuseppe, Dell'Orso, Stefania, Brooks, Stephen R., Furumoto, Yasuko, Thomas, Craig J., O'Shea, John J., Sciumè, Giuseppe, Gadina, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930870/
https://www.ncbi.nlm.nih.gov/pubmed/31921209
http://dx.doi.org/10.3389/fimmu.2019.02972