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The Effects of Terminal Tagging on Homomeric Interactions of the Sigma 1 Receptor
The sigma 1 receptor (σ1R) has been implicated in cancers, neurological disorders, and substance use disorders. Yet, its molecular and cellular functions have not been well-understood. Recent crystal structures of σ1R reveal a single N-terminal transmembrane segment and C-terminal ligand-binding dom...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930887/ https://www.ncbi.nlm.nih.gov/pubmed/31920515 http://dx.doi.org/10.3389/fnins.2019.01356 |