Erastin Reverses ABCB1-Mediated Docetaxel Resistance in Ovarian Cancer

Overexpression of drug efflux transport ABCB1 is correlated with multidrug resistance (MDR) among cancer cells. Upregulation of ABCB1 accounts for the recurrence of resistance to docetaxel therapy in ovarian cancer with poor survival. Erastin is a novel and specific small molecule that targets SLC7A...

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Detalles Bibliográficos
Autores principales: Zhou, Hai-Hong, Chen, Xu, Cai, Lu-Ya, Nan, Xing-Wei, Chen, Jia-Hua, Chen, Xiu-Xiu, Yang, Yang, Xing, Zi-Hao, Wei, Meng-Ning, Li, Yao, Wang, Sheng-Te, Liu, Kun, Shi, Zhi, Yan, Xiao-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930896/
https://www.ncbi.nlm.nih.gov/pubmed/31921655
http://dx.doi.org/10.3389/fonc.2019.01398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930896/
https://www.ncbi.nlm.nih.gov/pubmed/31921655
http://dx.doi.org/10.3389/fonc.2019.01398

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