Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr‐Cas9

BACKGROUND: Genetically engineered animals are essential for gaining a proper understanding of the disease mechanisms of cystic fibrosis (CF). The rat is a relevant laboratory model for CF because of its zootechnical capacity, size, and airway characteristics, including the presence of submucosal gl...

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Detalles Bibliográficos
Autores principales: Dreano, Elise, Bacchetta, Marc, Simonin, Juliette, Galmiche, Louise, Usal, Claire, Slimani, Lotfi, Sadoine, Jérémy, Tesson, Laurent, Anegon, Ignacio, Concordet, Jean‐Paul, Hatton, Aurélie, Vignaud, Lucile, Tondelier, Danielle, Sermet‐Gaudelus, Isabelle, Chanson, Marc, Cottart, Charles‐Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930998/
https://www.ncbi.nlm.nih.gov/pubmed/31942562
http://dx.doi.org/10.1002/ame2.12091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930998/
https://www.ncbi.nlm.nih.gov/pubmed/31942562
http://dx.doi.org/10.1002/ame2.12091

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