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Nuclear magnetic resonance based structure of the protoberberine alkaloid coralyne and its self-association by spectroscopy techniques
Coralyne is an important alkaloid due to its anti-cancer and other medicinal properties. It targets DNA in cells and acts as human topoisomerase-I poison, telomerase inhibitor and nucleic acid intercalator. It has high tendency to undergo self-association, which is a matter of concern for therapeuti...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Xi'an Jiaotong University
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931075/ https://www.ncbi.nlm.nih.gov/pubmed/31890344 http://dx.doi.org/10.1016/j.jpha.2019.09.006 |