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Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples
Methotrexate (MTX) is a folate antagonist drug used for several diseases, such as cancers, various malignancies, rheumatoid arthritis (RA) and inflammatory bowel disease. Due to its structural features, including the presence of two carboxylic acid groups and its low native fluorescence, there are s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Xi'an Jiaotong University
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931080/ https://www.ncbi.nlm.nih.gov/pubmed/31890337 http://dx.doi.org/10.1016/j.jpha.2019.06.001 |