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Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Methotrexate (MTX) is a folate antagonist drug used for several diseases, such as cancers, various malignancies, rheumatoid arthritis (RA) and inflammatory bowel disease. Due to its structural features, including the presence of two carboxylic acid groups and its low native fluorescence, there are s...

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Detalles Bibliográficos
Autores principales: Karami, Forough, Ranjbar, Sara, Ghasemi, Younes, Negahdaripour, Manica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931080/
https://www.ncbi.nlm.nih.gov/pubmed/31890337
http://dx.doi.org/10.1016/j.jpha.2019.06.001

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