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Impairment of natriuresis and diuresis induced by intrarenal adrenoceptor mechanisms in an experimental model of cirrhosis in rats

The contribution of intrarenal alpha-2 adrenergic receptors in mediating the enhanced renal excretory responses evoked by the alpha-2-agonist xylazine was examined in a model of cirrhosis in rats. In sham-operated rats, xylazine (0.2 mg/kg, i.v.) increased diuresis and natriuresis (urine flow, contr...

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Detalles Bibliográficos
Autores principales: Milanez, Maycon I.O., Cabral, Antônio M., Pires, José G.P., Bergamaschi, Cássia T., Campos, Ruy R., Futuro Neto, Henrique A., Silva, Nyam F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931082/
https://www.ncbi.nlm.nih.gov/pubmed/31890977
http://dx.doi.org/10.1016/j.heliyon.2019.e03066