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Dual-Isotope SPECT Imaging with NIS Reporter Gene and Duramycin to Visualize Tumor Susceptibility to Oncolytic Virus Infection

Noninvasive dual-imaging methods that provide an early readout on tumor permissiveness to virus infection and tumor cell death could be valuable in optimizing development of oncolytic virotherapies. Here, we have used the sodium iodide symporter (NIS) and (125)I radiotracer to detect infection and r...

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Detalles Bibliográficos
Autores principales: Zhang, Lianwen, Suksanpaisan, Lukkana, Jiang, Huailei, DeGrado, Timothy R., Russell, Stephen J., Zhao, Ming, Peng, Kah-Whye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931109/
https://www.ncbi.nlm.nih.gov/pubmed/31890867
http://dx.doi.org/10.1016/j.omto.2019.10.002