Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation

Oncolytic viruses represent an emerging approach to cancer therapy. However, better understanding of their interaction with the host cancer cell and approaches to enhance their efficacy are needed. Here, we investigate the effect of chemically induced endoplasmic reticulum (ER) stress on the activit...

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Detalles Bibliográficos
Autores principales: Taverner, William K., Jacobus, Egon J., Christianson, John, Champion, Brian, Paton, Adrienne W., Paton, James C., Su, Weiheng, Cawood, Ryan, Seymour, Len W., Lei-Rossmann, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931121/
https://www.ncbi.nlm.nih.gov/pubmed/31890865
http://dx.doi.org/10.1016/j.omto.2019.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931121/
https://www.ncbi.nlm.nih.gov/pubmed/31890865
http://dx.doi.org/10.1016/j.omto.2019.09.003

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