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Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation
Oncolytic viruses represent an emerging approach to cancer therapy. However, better understanding of their interaction with the host cancer cell and approaches to enhance their efficacy are needed. Here, we investigate the effect of chemically induced endoplasmic reticulum (ER) stress on the activit...
Autores principales: | Taverner, William K., Jacobus, Egon J., Christianson, John, Champion, Brian, Paton, Adrienne W., Paton, James C., Su, Weiheng, Cawood, Ryan, Seymour, Len W., Lei-Rossmann, Janet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931121/ https://www.ncbi.nlm.nih.gov/pubmed/31890865 http://dx.doi.org/10.1016/j.omto.2019.09.003 |
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