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PDZ-Binding Kinase-Dependent Transcriptional Regulation of CCNB2 Promotes Tumorigenesis and Radio-Resistance in Glioblastoma

Increasing evidence has indicated that PDZ binding kinase (PBK) promotes proliferation, invasion, and therapeutic resistance in a variety of cancer types. However, the physiological function and therapy-resistant role of PBK in GBM remain underexplored. In this study, PBK was identified as one of th...

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Detalles Bibliográficos
Autores principales: Mao, Ping, Bao, Gang, Wang, Yi-Chang, Du, Chang-Wang, Yu, Xiao, Guo, Xiao-Ye, Li, Rui-Chun, Wang, Mao-De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931196/
https://www.ncbi.nlm.nih.gov/pubmed/31874375
http://dx.doi.org/10.1016/j.tranon.2019.09.011