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Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain

Proteostasis is critical for cells to maintain the balance between protein synthesis, quality control, and degradation. This is particularly important for myeloid cells of the central nervous system as their immunological function relies on proper intracellular protein turnover by the ubiquitin-prot...

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Detalles Bibliográficos
Autores principales: Studencka-Turski, Maja, Çetin, Gonca, Junker, Heike, Ebstein, Frédéric, Krüger, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932173/
https://www.ncbi.nlm.nih.gov/pubmed/31921161
http://dx.doi.org/10.3389/fimmu.2019.02900