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Loss of autophagy impairs physiological steatosis by accumulation of NCoR1

Lipid droplets (LDs) are dynamic organelles that store neutral lipids during times of energy excess, such as after a meal. LDs serve as an energy reservoir during fasting and have a buffering capacity that prevents lipotoxicity. Autophagy and the autophagic machinery have been proposed to play a rol...

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Detalles Bibliográficos
Autores principales: Takahashi, Shun-saku, Sou, Yu-Shin, Saito, Tetsuya, Kuma, Akiko, Yabe, Takayuki, Sugiura, Yuki, Lee, Hyeon-Cheol, Suematsu, Makoto, Yokomizo, Takehiko, Koike, Masato, Terai, Shuji, Mizushima, Noboru, Waguri, Satoshi, Komatsu, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932742/
https://www.ncbi.nlm.nih.gov/pubmed/31879337
http://dx.doi.org/10.26508/lsa.201900513