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AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes

Gene editing strategies, such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeat/Cas9 (CRISPR/Cas9), are revolutionizing biology. However, quantitative and sensitive detection of targeted mutations a...

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Detalles Bibliográficos
Autores principales: Bruyneel, Arne A. N., Colas, Alexandre R., Karakikes, Ioannis, Mercola, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932767/
https://www.ncbi.nlm.nih.gov/pubmed/31877162
http://dx.doi.org/10.1371/journal.pone.0226694