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Molecular sampling at logarithmic rates for next-generation sequencing

Next-generation sequencing is a cutting edge technology, but to quantify a dynamic range of abundances for different RNA or DNA species requires increasing sampling depth to levels that can be prohibitively expensive due to physical limits on molecular throughput of sequencers. To overcome this prob...

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Detalles Bibliográficos
Autores principales: Horn, Caroline, Salzman, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932819/
https://www.ncbi.nlm.nih.gov/pubmed/31830035
http://dx.doi.org/10.1371/journal.pcbi.1007537