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Genomic landscapes by multiregion sequencing combined with circulation tumor DNA detection contribute to molecular diagnosis in glioblastomas

Glioblastoma is a highly aggressive brain malignancy with a poor prognosis. Its high intratumor heterogeneity contributes to therapeutic resistance, tumor progression and recurrence. We sequenced 31 loci in 11 patients with glioblastoma (including one patient with samples available from the primary...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Tan, Yanli, Li, Shouwei, Zhou, Junhu, Wang, Qixue, Wang, Yunfei, Xie, Yingbin, Chen, Luyue, Li, Jie, Fang, Chuan, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932900/
https://www.ncbi.nlm.nih.gov/pubmed/31822636
http://dx.doi.org/10.18632/aging.102526