Melatonin protects blood-brain barrier integrity and permeability by inhibiting matrix metalloproteinase-9 via the NOTCH3/NF-κB pathway

The pathophysiological mechanism of white matter hyperintensities of cerebral small vessel disease (CSVD) includes an impaired blood-brain barrier (BBB) with increased permeability. Neuroinflammation likely contributes to the disruption of the BBB in CSVD. Therefore, understanding the molecular mech...

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Detalles Bibliográficos
Autores principales: Qin, Weiwei, Li, Jing, Zhu, Rongjia, Gao, Suhua, Fan, Junfen, Xia, Mingrong, Zhao, Robert Chunhua, Zhang, Jiewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932927/
https://www.ncbi.nlm.nih.gov/pubmed/31811815
http://dx.doi.org/10.18632/aging.102537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932927/
https://www.ncbi.nlm.nih.gov/pubmed/31811815
http://dx.doi.org/10.18632/aging.102537

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