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Novel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function

BACKGROUND AND PURPOSE: Asthenozoospermia is a leading cause of male infertility, but development of pharmacological agents to improve sperm motility is hindered by the lack of effective screening platforms and knowledge of suitable molecular targets. We have demonstrated that a high‐throughput scre...

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Detalles Bibliográficos
Autores principales: McBrinn, Rachel C., Fraser, Joanna, Hope, Anthony G., Gray, David W., Barratt, Christopher L.R., Martins da Silva, Sarah J., Brown, Sean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932944/
https://www.ncbi.nlm.nih.gov/pubmed/31368510
http://dx.doi.org/10.1111/bph.14814