Paracrine Fibroblast Growth Factor 1 Functions as Potent Therapeutic Agent for Intrahepatic Cholestasis by Downregulating Synthesis of Bile Acid

Endocrine fibroblast growth factor (FGF) 19 has been shown to be capable of maintaining bile acid (BA) homeostasis and thus hold promise to be a potential therapeutic agent for cholestasis liver disease. However, whether paracrine FGFs possess this BA regulatory activity remains to be determined. In...

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Detalles Bibliográficos
Autores principales: Lin, Huan, Zhou, Chuanren, Hou, Yushu, Li, Qi, Qiao, Guanting, Wang, Yang, Huang, Zhifeng, Niu, Jianlou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933012/
https://www.ncbi.nlm.nih.gov/pubmed/31920680
http://dx.doi.org/10.3389/fphar.2019.01515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933012/
https://www.ncbi.nlm.nih.gov/pubmed/31920680
http://dx.doi.org/10.3389/fphar.2019.01515

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