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Paracrine Fibroblast Growth Factor 1 Functions as Potent Therapeutic Agent for Intrahepatic Cholestasis by Downregulating Synthesis of Bile Acid
Endocrine fibroblast growth factor (FGF) 19 has been shown to be capable of maintaining bile acid (BA) homeostasis and thus hold promise to be a potential therapeutic agent for cholestasis liver disease. However, whether paracrine FGFs possess this BA regulatory activity remains to be determined. In...
Autores principales: | Lin, Huan, Zhou, Chuanren, Hou, Yushu, Li, Qi, Qiao, Guanting, Wang, Yang, Huang, Zhifeng, Niu, Jianlou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933012/ https://www.ncbi.nlm.nih.gov/pubmed/31920680 http://dx.doi.org/10.3389/fphar.2019.01515 |
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