BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice

OBJECTIVE: Bone morphogenetic protein 4 (BMP4) adeno-associated viral vectors of serotype 8 (AAV8) gene therapy targeting the liver prevents the development of obesity in initially lean mice by browning the large subcutaneous white adipose tissue (WAT) and enhancing energy expenditure. Here, we exam...

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Detalles Bibliográficos
Autores principales: Hoffmann, Jenny M., Grünberg, John R., Hammarstedt, Ann, Kroon, Tobias, Greiner, Thomas U., Maurer, Stefanie, Elias, Ivet, Palsdottir, Vilborg, Bosch, Fatima, Boucher, Jeremie, Hedjazifar, Shahram, Smith, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933264/
https://www.ncbi.nlm.nih.gov/pubmed/32029225
http://dx.doi.org/10.1016/j.molmet.2019.11.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933264/
https://www.ncbi.nlm.nih.gov/pubmed/32029225
http://dx.doi.org/10.1016/j.molmet.2019.11.016

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