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Labile Heme Aggravates Renal Inflammation and Complement Activation After Ischemia Reperfusion Injury

Background: Ischemia reperfusion injury (IRI) plays a major role in solid organ transplantation. The length of warm ischemia time is critical for the extent of tissue damage in renal IRI. In this experimental study we hypothesized that local release of labile heme in renal tissue is triggered by the...

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Detalles Bibliográficos
Autores principales: Wang, Li, Vijayan, Vijith, Jang, Mi-Sun, Thorenz, Anja, Greite, Robert, Rong, Song, Chen, Rongjun, Shushakova, Nelli, Tudorache, Igor, Derlin, Katja, Pradhan, Pooja, Madyaningrana, Kukuh, Madrahimov, Nodir, Bräsen, Jan Hinrich, Lichtinghagen, Ralf, van Kooten, Cees, Huber-Lang, Markus, Haller, Hermann, Immenschuh, Stephan, Gueler, Faikah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933315/
https://www.ncbi.nlm.nih.gov/pubmed/31921212
http://dx.doi.org/10.3389/fimmu.2019.02975