Cargando…

p53‐dependent transcriptional suppression of BAG3 protects cells against metabolic stress via facilitation of p53 accumulation

Solid tumour frequently undergoes metabolic stress during tumour development because of inadequate blood supply and the high nutrient expenditure. p53 is activated by glucose limitation and maintains cell survival via triggering metabolic checkpoint. However, the exact downstream contributors are no...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jia‐Mei, Liu, Bao‐Qin, Du, Zhen‐Xian, Li, Chao, Sun, Jia, Yan, Jing, Jiang, Jing‐Yi, Wang, Hua‐Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933324/
https://www.ncbi.nlm.nih.gov/pubmed/31657880
http://dx.doi.org/10.1111/jcmm.14764