Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence

Glioma is a common brain malignancy for which new drug development is urgently needed because of radiotherapy and drug resistance. Recent studies have demonstrated that artemisinin (ARS) compounds can display antiglioma activity, but the mechanisms are poorly understood. Using cell lines and mouse m...

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Detalles Bibliográficos
Autores principales: Wei, Shupei, Liu, Lili, Chen, Zhiyu, Yin, Wenli, Liu, Yingzi, Ouyang, Qianying, Zeng, Feiyue, Nie, Yingjie, Chen, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933330/
https://www.ncbi.nlm.nih.gov/pubmed/31746143
http://dx.doi.org/10.1111/jcmm.14717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933330/
https://www.ncbi.nlm.nih.gov/pubmed/31746143
http://dx.doi.org/10.1111/jcmm.14717

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